Osmond Gilles (24 August 1788 – 25 September 1866) was a settler, pastoralist, mine owner and South Australia’s first colonial treasurer.
After several years of working in Hamburg, Germany as a merchant, Gilles migrated to the new Australian colony on the HMS Buffalo in 1836 and acted as the Colonial Treasurer. He was a prominent businessman and land owner, with the largest holdings of any settler in 1837, and sat on the Street Naming Committee on 23 May, 1837.
He is remembered by Gilles Street in the Adelaide Central Business District, Glen Osmond Road, OG Road and the Adelaide suburbs of Glen Osmond and Gilles Plains.